The Terriers travel to Toughsheet Community Stadium on Tuesday, December 10 (7:45 p.m.).
Ian Evatt's men were assured of a home draw after finishing top of their group thanks to wins against Barrow and Fleetwood.
Meanwhile, the Yorkshire club finished second behind Doncaster with wins over Barnsley and Manchester United U21.
Tickets cost £10 for adults and £5 for over-65s and under-18s when the knockout stages get underway.
They can be purchased online via the official website, in person at the box office or via the telephone lines on 01204 328888. Only the lower level of the Nat Lofthouse Stand will be open for the match.
Huddersfield currently sit fifth in League One as they look to bounce back from relegation from the Championship last season.
Michael Duff's side are unbeaten in their last seven league matches, including back-to-back wins against Charlton and Leyton Orient.
The Trophy was renamed last week after Vertu – the group that currently operates under the names of three brands, including Bristol Street Motors – announced it would merge those brands into one.
The knockout stages remain regionalized between the Northern and Southern sections until the quarter-final, with draws going straight to penalties if the scores are level after 90 minutes.
Wanderers reached the last eight before losing on penalties at Blackpool last season. Twelve months earlier they went all out after a memorable win against Plymouth at Wembley.